New Indole Alkaloids from Kopsia Singapurensis (RIDL.)
نویسندگان
چکیده
منابع مشابه
Antitussive indole alkaloids from Kopsia hainanensis.
Three new indole alkaloids, named kopsihainins A-C (1-3), and two known compounds, kopsinine (4) and methyl demethoxycarbonylchanofruticosinate (5), were isolated from the stems of Kopsia hainanensis. Their structures were determined using extensive spectroscopic methods. The two main constituents 4 and 5 exhibited significant antitussive activity in a citric acid induced guinea pig cough model...
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Three new indole alkaloids (1-3), named grandilodines A-C, and five known ones were obtained from the Malayan Kopsia grandifolia. The structures were established using NMR and MS analyses and, in the case of 1 and 2, were confirmed by X-ray diffraction analyses. Alkaloids 1, 3, and lapidilectine B (8) were found to reverse multidrug resistance in vincristine-resistant KB cells.
متن کاملIndole Alkaloids from Chaetomium globosum.
Two new indole alkaloids chaetocochin J (1) and chaetoglobinol A (8), along with chetomin (2), chetoseminudin A (3), cochliodinol (9), and semicochliodinol (10), were isolated from the rice culture of the fungus Chaetomium globosum. Their structures were elucidated by spectral analysis. Three new epipolythiodioxopiperazines, chaetocochins G-I (5-7), were identified by the combination of UPLC an...
متن کاملCorynanthean, eburnan, secoleuconoxine, and pauciflorine alkaloids from Kopsia pauciflora.
Eleven indole alkaloids, comprising four corynanthean, two eburnane, one aspidofractinine, one secoleuconoxine, one andranginine, and two pauciflorine type alkaloids were isolated from the stem-bark and leaf extracts of Kopsia pauciflora. Their structures were determined using NMR and MS analyses. The catharinensine type alkaloid kopsirensine B and the secoleuconoxine alkaloid arboloscine A sho...
متن کاملKopsihainanines A and B, two unusual alkaloids from Kopsia hainanensis.
Kopsihainanine A (1), an unprecedented skeleton with a 6/5/6/6/6 pentacyclic rearranged ring system, together with a new biogenetically related compound, kopsihainanine B (2), were isolated from Kopsia hainanensis. Their structures were elucidated by means of spectroscopic methods. The absolute configuration of 1 was determined by ECD calculation.
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ژورنال
عنوان ژورنال: The Open Conference Proceedings Journal
سال: 2013
ISSN: 2210-2892
DOI: 10.2174/2210289201304020075